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In biological experiments, 'cell lysis' is a seemingly fundamental but extremely critical step. Whether it's extracting protein DNA、RNA， Whether to prepare cell homogenate or not, the efficiency and method of cell lysis in the early stage often determine the success or failure of subsequent experiments.
Although traditional cell disruptors have stable performance, they are bulky and limited in operation, making them unsuitable for work scenarios with small sample sizes, high experimental frequencies, and strong site flexibility. Nowadays, the emergence of handheld ultrasonic cell disruptors has precisely solved this pain point.
1、 Flexible operation, more convenient for small sample processing
In experiments, it is common to encounter scenarios where only one or two 1.5mL centrifuge tube samples need to be processed. Starting with large equipment is time-consuming, cleaning is cumbersome, and it also occupies valuable operational space.
Handheld devices are compact in size and can be operated with just one hand, without the need to connect large brackets and complex accessories. Especially suitable for:
Rapid fragmentation of small cell samples
Laboratory teaching and student practical training scenarios
Mobile applications such as mobile testing and field sample processing
2、 Ready to use, improving experimental efficiency
Compared to traditional equipment that requires preheating, frequency regulation, and waiting for operation, handheld ultrasonic crushers often adopt a one click start design, with the time and power set for operation.
For time sensitive experiments such as RNA extraction, this saves valuable sample activity and research window period.
3、 Ultrasonic energy concentration, high crushing efficiency
Despite its small size, handheld ultrasound devices are not inferior in terms of energy output. By high-frequency oscillation (commonly 20-40kHz), cell membrane structure rupture can be achieved, releasing intracellular components.
Suitable for crushing and processing various biological materials, such as:
Animal and plant tissue
Microbial cells (such as Escherichia coli, yeast)
Animal cells, plant cells
Virus particles, etc
4、 Lower sample cross contamination and simpler cleaning
Handheld devices are usually used in conjunction with miniature probes and disposable centrifuge tubes to avoid cross contamination between samples. The cleaning process is simple, just wipe or replace the probe, especially suitable for high-throughput laboratories to quickly switch sample types.
5、 Easy to carry, compatible with multiple scenarios
With the gradual diversification of experimental forms, some work requires on-site sampling and preliminary on-site processing. Handheld ultrasonic cell disruptors have become an ideal choice for mobile experimental vehicles, field work, hospital real-time processing, and other scenarios due to their strong portability and flexible power supply (some models support battery power or low-voltage adapters).
Conclusion:
In scientific research, optimizing every experimental step is a guarantee of the reliability of the results.
The Shanghai Yetuo handheld ultrasonic cell disruptor, with its flexibility, low pollution, and easy operation, has brought more convenience and possibilities to experiments.
It is not the protagonist, but it makes experiments smoother, data more reliable, and allows researchers more time to focus on truly important thoughts and discoveries.
